Endocrine Abstracts

The mineralocorticoid receptor (MR) is primarily involved in osmoregulation in mammals, with additional roles of brain-behaviour implicated. However, the understanding of this role is limited, partly due to the mortality of MR-knockout mice due to impaired Na+ reabsorption. Many steroidogenesis pathways and hormone receptors are highly conserved in zebrafish, providing a great potential to become a high-throughput model for translational endocrine research. My proje...